. 2011 Jun 1;15(3):381–390. doi: 10.1007/s10157-011-0418-0

Table 2.

Association between SNPs in SIRT2 and diabetic nephropathy

	Allele frequencies (nephropathy case−control)
	Proteinuria				ESRD	Combined
	Study 1	Study 2	P	OR (95% CI)	Study 3	P	OR (95% CI)
SNP
rs1001413^a G>A	0.381/0.359	0.353/0.361	0.594	1.03 (0.91–1.17)	0.342/0.389	0.837	0.99 (0.88–1.11)
rs892034^a C>T	0.193/0.166	0.180/0.169	0.099	1.14 (0.98–1.34)	0.164/0.194	0.352	1.07 (0.93–1.23)
rs2015^a A>C	0.398/0.400	0.389/0.406	0.550	0.96 (0.85–1.09)	0.384/0.391	0.522	0.96 (0.86–1.08)
rs2241703^a G>A	0.235/0.226	0.222/0.215	0.534	1.05 (0.91–1.21)	0.219/0.208	0.453	1.05 (0.92–1.20)
rs2082435^a C>G	0.247/0.262	0.260/0.270	0.365	0.94 (0.82–1.08)	0.256/0.231	0.678	0.97 (0.86–1.10)
rs11575003^a T>C	0.118/0.115	0.126/0.132	0.886	0.99 (0.82–1.18)	0.132/0.119	0.887	1.01 (0.86–1.19)
rs2053071^a G>C	0.377/0.398	0.384/0.396	0.260	0.93 (0.82–1.05)	0.426/0.402	0.506	0.96 (0.86–1.08)
Haplotype
Block 1
CCGG	0.243/0.258	0.245/0.268	0.136	0.90 (0.79–1.03)	0.254/0.226	0.366	0.95 (0.84–1.07)
CAAC	0.231/0.222	0.227/0.216	0.438	1.06 (0.92–1.22)	0.218/0.204	0.347	1.06 (0.94–1.21)
CAGC	0.179/0.212	0.207/0.206	0.186	0.91 (0.78–1.05)	0.232/0.205	0.477	0.95 (0.84–1.09)
TAGC	0.191/0.165	0.191/0.169	0.037	1.18 (1.01–1.37)	0.164/0.197	0.196	1.10 (0.95–1.26)
CCGC	0.154/0.142	0.127/0.140	0.993	0.999 (0.84–1.18)	0.130/0.164	0.497	0.95 (0.81–1.04)
Block 2
TG	0.620/0.597	0.614/0.599	0.191	1.08 (0.96–1.22)	0.568/0.585	0.346	1.05 (0.95–1.17)
TC	0.262/0.288	0.256/0.270	0.142	0.91 (0.79–1.03)	0.300/0.295	0.121	0.91 (0.81–1.02)
CC	0.114/0.110	0.126/0.127	0.850	1.02 (0.85–1.22)	0.127/0.109	0.586	1.05 (0.89–1.23)

Block 1; rs892034, rs2015, rs2241703, rs2082435

Block 2; rs11575003, rs2053071

^aTag SNPs