Table 1.
Bronchoalveolar lavage (BAL) cellular response following antibody treatment during chronic antigen challenge
| Groups | Naive | Control | Anti-IL-4 | Anti-IL-25 |
|---|---|---|---|---|
| Total | 121 (14·8) | 220 (43·9) | 199 (28·5) | 141 (19·7) |
| Macrophages | 94·5% (0·8) | 86·6% (1·7)* | 91·8% (2·2) | 84·0% (2·5)## |
| Lymphocytes | 4·4% (0·9) | 12·7% (1·6)*** | 6·0% (1·5)## | 5·0% (1·0)## |
| Neutrophil | 0·6% (0·2) | 3·0% (0·3) | 0·4% (0·2) | 8·5% (2·1)*** ## |
| Eosinophils | 0% (0·0) | 0·3% (0·1)** | 0% (0·0)## | 0% (0·0)## |
Data are presented as mean numbers of cells (thousands) ± standard error of the mean and as percentages for individual cell types (n = 8). Significant differences compared to naive animals shown as * P < 0·05, **P < 0·01 and ***P < 0·001, compared to control animals shown as ##P < 0·01. IL: interleukin.