Fig. 2.

Left column: prothrombin fragment F1+2 and d-dimer levels in the blister fluid and plasma of 63 patients with bullous pemphigoid (BP) and the plasma of 40 normal controls. The horizontal lines represent median values. F1+2 and d-dimer levels were both much higher in the blister fluid of the BP patients than in their plasma or in the plasma of the controls. Right column: plasma prothrombin fragment F1+2 and d-dimer levels in 16 patients with bullous pemphigoid (BP) before and after immunosuppressive therapy leading to complete remission, when there were marked reductions in both. Statistical significances refer to both parameters.