Table 4.
Changes at the Protein Level after Addition of 125 ng/mL of Novobiocin
| No. | Gene product | Fold change protein (mRNA) | ||
|---|---|---|---|---|
| 10 min | 30 min | 60 min | ||
| hi0048 | Oxidoreductase | −3.1 (NC) | −3.5 (NC) | −1.7 (NC) |
| hi0089 | Aspartokinase I/homoserine dehydrogenase I | −2.6 (−3.4) | −1.3 (NC) | −2.0 (−2.0) |
| hi0119 | Adhesin B precursor | −261.8 (NC) | −12.8 (−2.8) | −34.1 (−2.7) |
| hi0124 | Inorganic pyrophosphatase | −2.1 (1.2) | −3.3 (NC) | −5.4 (NC) |
| hi0504 | Periplasmic ribose-binding protein | −1.8 (−2.2) | −2.5 (−3.9) | −3.5 (−1.9) |
| hi0524 | Fructose-bisphosphate aldolase | 2.0 (1.8) | 2.1 (1.6) | 1.0 (1.9) |
| hi0525 | Phosphoglycerate kinase | −2.0 (2.2) | −2.1 (2.1) | −2.9 (2.0) |
| hi0542 | Heat shock protein GroES | −1.9 (−2.3) | −4.4 (−4.6) | −3.5 (−3.7) |
| hi0544 | Ribosomal protein L9 | −3.5 (−1.5) | −2.0 (−1.7) | −3.6 (NC) |
| hi0547 | Ribosomal protein S6 | −4.2 (NC) | −2.1 (NC) | −2.7 (NC) |
| hi0553 | 6-Phosphogluconate dehydrogenase, decarboxylating | −5.5 (NC) | −4.4 (NC) | −3.2 (NC) |
| hi0574 | Conserved hypothetical protein | −3.8 (−2.1) | −3.8 (−2.9) | −4.0 (−2.3) |
| hi0808 | Ribosome releasing factor | −4.7 (−4.5) | −4.4 (−5.4) | −4.7 (−4.9) |
| hi0846 | Disulfide oxidoreductase | −2.6 (NC) | −2.0 (−1.9) | −2.4 (−2.1) |
| hi0913 | Ribosomal protein S2 | −2.3 (NC) | −3.8 (−2.4) | −5.2 (−2.2) |
| hi0914 | Elongation factor EF-Ts | −4.2 (NC) | −5.5 (−3.0) | −2.9 (−2.6) |
| hi0927 | Glycyl-tRNA synthetase alpha chain | 2.5 (NC) | 2.9 (1.5) | −1.2 (1.6) |
| hi1228 | Uracil phosphoribosyltransferase | −3.0 (−2.0) | −3.2 (−2.2) | −3.4 (−2.0) |
| hi1507 | Hypothetical protein | −4.1 (1.3) | −3.2 (−3.5) | −2.9 (−3.2) |
| hi1647 | Conserved hypothetical protein | −2.0 (−2.3) | −1.8 (−1.8) | −2.3 (−1.6) |
| hi1734 | Enoyl-reductase | −8.8 (−2.6) | −7.2 (−2.6) | −6.2 (−2.1) |