. 2011 Apr 1;2(2):145–155.

Table 5.

The association between 16 tagSNPs and risk for NSCLC in the New Mexico study

miRs/Genes/SNPs	Genotype ^a	Controls	Cases	OR (95% CI) ^b
miR-200c-141 cluster
rs74057236 ^c	C/C	419	302	1.0
	C/T & T/T	75	60	1.12(0.76-1.65)
M2C1N2	Undel/Undel	449	324	1.0
	Undel/Del	58	41	1.03(0.66-1.61)
rs16933011 ^c	G/G	404	312	1.0
	G/T & T/T	87	50	0.75(0.51-1.11)
miR-200b-a-429 cluster
rs1539636 ^c	G/G	384	292	1.0
	G/A & A/A	89	66	1.06(0.73-1.53)
rs1539635 ^c	A/A	202	151	1.0
	G/A	215	163	0.98(0.72-1.32)
	G/G	67	51	0.88(0.57-1.38)
rs61768478 ^c	G/G	284	211	1.0
	G/T	158	123	0.96(0.70-1.30)
	T/T	31	24	0.86(0.47-1.56)
rs61768479 ^c	C/C	433	341	1.0
	C/G & G/G	52	24	0.50 (0.30-0.85) ^d
rs12135382 ^c	T/T	167	125	1.0
	T/C	216	171	1.04(0.76-1.43)
	C/C	90	64	0.82(0.54-1.24)
rs35668979	G/G	458	351	1.0
	G/A	24	14	0.83(0.42-1.66)
rs1891905	T/T	400	311	1.0
	T/C & C/C	72	51	0.94(0.62-1.40)
rs7518873	C/C	397	294	1.0
	C/T & T/T	97	68	1.02(0.71-1.47)
M2BA429N3	T/T	456	342	1.0
	T/C & C/C	28	22	0.94(0.52-1.70)
miR-205/rs2249632	G/G	215	163	1.0
	G/A	218	141	0.90(0.66-1.22)
	A/A	56	50	1.01(0.64-1.59)
E-cadherin
rs16260 ^c	C/C	223	189	1.0
	C/A	201	143	0.81(0.48-1.35)
	A/A	48	30	0.84(0.62-1.13)
rs45625236 ^c	Undel/Undel	399	282	1.0
	Undel/Del	93	80	1.20(0.85-1.70)
ZEB1/rs7349	C/C	422	307	1.0
	C/T & T/T	63	57	1.24(0.82-1.88)

To ensure adequate statistical power, SNPs with MAF ≤ 0.11 were tested under a dominant model and SNPs with MAF > 0.11 were tested under a co-dominant model

Age, gender, ethnicity, current smoking status, and packyears were included as adjustment factors in an unconditional logistic regression model

These SNPs were selected as htSNPs

P=0.01.