Table 3.
miRNA expression in DC SH-SY5Y cells after exposure to TNF-α
| 15mins | miR-128a 2-ΔΔCt geometric mean | miR-128b 2-ΔΔCt geometric mean | miR-27a 2-ΔΔCt geometric mean | miR-27b 2-ΔΔCt geometric mean | let-7a 2-ΔΔCt geometric mean | let-7b 2-ΔΔCt geometric mean | miR-155 2-ΔΔCt geometric mean |
|---|---|---|---|---|---|---|---|
| 1 ngTNF-α | 0.53 | 1.13 | 1.11 | 1.07 | 0.03 | 0.44 | 0.07 |
| 10ngTNF-α | 1.3 | 0.88 | 1.52 | 1.5 | 0.42 | 0.4 | 0.03 |
| 50ngTNF-α | 2.0 | 1.08 | 1.81 | 2.39 | 1.32 | 0.78 | 0.04 |
| 3h | |||||||
| 1 ngTNF-α | 1.18 | 0.37 | 1.19 | 1.19 | 0.76 | 1.02 | 0.16 |
| 10ngTNF-α | 1.2 | 0.38 | 0.74 | 0.85 | 0.57 | 1.31 | 0.11 |
| 50ngTNF-α | 1 | 0.54 | 1.05 | 1.15 | 1.45 | 1.35 | 0.32 |