Table 1.
Gene Information
| Name | GeneID | RefSeq | Chr | Str | Start (bp) | Size (bp) | Description | tagSNP Source | Bin Coverage | N SNPs Analyzed (Attempted) |
|---|---|---|---|---|---|---|---|---|---|---|
| GSTM1 | 2944 | NM_000561.3 | 1 | + | 110,031,965 | 5,925 | Glutathione S-transferase M1 | HapMap | 100% | 1 (1) |
| XPC | 7508 | NM_004628.4 | 3 | + | 14,161,648 | 33,495 | Xeroderma pigmentosum, complementation group C | HapMap | 85% | 11 (11) |
| ABCB1 | 5243 | NM_000927.3 | 7 | + | 86,970,884 | 209,616 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | HapMap | 91% | 33 |
| CYP3A4 | 1576 | NM_017460.3 | 7 | + | 99,192,540 | 27,204 | Cytochrome P450, family 3, subfamily A, polypeptide 4 | NIEHS SNPs | 63% | 5 (5) |
| CYP2C8 | 1558 | NM_000770.3 | 10 | - | 96,786,519 | 32,725 | Cytochrome P450, family 2, subfamily C, polypeptide 8 | HapMap | 92% | 14 (14) |
| XRCC1 | 7515 | NM_006297.2 | 19 | + | 48,739,304 | 32,251 | X-ray repair complementing defective repair in Chinese hamster cells 1 | HapMap | 100% | 16 (16) |
| ERCC2 | 2068 | NM_000400.3 | 19 | + | 50,546,686 | 18,983 | Excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D) | HapMap | 85% | 11 (11) |
| ERCC1 | 2067 | NM_001983.2 | 19 | + | 50,604,712 | 14,305 | Excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) | HapMap | 60% | 3 (5) |
| Total | 94 (96) | |||||||||
Genome build 36.3; Refseq Release 29; chr, chromosome, str, strand, bp, base pairs; N analyzed SNPs excludes two (2%) which failed genotyping; sorted by chromosomal position; bin coverage calculated as number of bins with one or more tagSNPs successfully genotyped divided by the number of total bins (SNPs failed either due to incompatibility with assay design or to genotype failure).