Table 3. Clinical characteristics of the myocilin mutation in China glaucoma families.
|
|
|
|
|
|
Age at diagnosis (years) |
IOP max before treatment (mmHg) |
||
|---|---|---|---|---|---|---|---|---|
| Mutation type | Reference | Family -base | City in China | Phenotype | Mean (range) | Proband | Mean (range) | Proband |
| P370L |
Present study |
yes |
Puning in South China |
JOAG |
17 (9–28) |
21 |
34.18 (29–40) |
45 |
| P370L |
[12] |
yes |
Guangzhou in South China |
JOAG |
30 (11–35) |
20 |
45.52 (35–56) |
37 |
| P370L |
[13] |
yes |
Shanghai in East China |
JOAG |
22.6 (14–31) |
20 |
41 (30–54) |
46 |
| Q337X |
[14] |
yes |
Shanghai in East China |
JOAG |
24.9 (16–41) |
41 |
30.8 (24–46) |
28 |
| C 245Y |
[15] |
yes |
hongkong |
JOAG |
18 (12–27) |
16 |
26 (24–26) |
26 |
| N450Y | [16] | yes | Beijing in North China | JOAG | 26.3 (20–31) | 20 | 48.5 (30–56) | N/A |