Table 4.

SNPs That Do Not Alter Protein Sequence^a

Gene	Exon/Intron	NT change	Position	Comments
ACAT2	Ex6	CTG→CTT	609G→Tb
	Ex6	CTA→TTA	610C→T
CH25H	Ex1	CTG→CTC	54G→C
	Ex1	AAC→AAT	657C→T
CLA1	Ex8	GCC→GCT	1050C→T	Acton et al. 1999
LDLR	Ex2	TGT→TGC	81T→C	Soutar et al. 1991
	EX2	AAC→AAT	90C→T
	Ex10	AGG→AGA	1413G→A	Warnich et al. 1992
	Ex11	CCC→CCT	1617C→T	Leren et al. 1992
	Ex12	CTC→CTT	1725C→T	Yamakawa et al. 1993
	Ex12	AAT→AAC	1773T→C	Chaves et al. 1991
	Ex13	GTC→GTT	1959C→T	Hobbs et al. 1987
NR1H2	Ex3	AGC→AGT	297C→T
S-1-P	Ex11	CCC→CCT	1317C→T
	Ex11	CTC→CTT	1407C→T
	In23d	G→A	IVS23+7G→Ac
SCAP	Ex15	ATC→ATA	2031C→A
	Ex20	TCG→TCT	3321G→T
SREBF-1	In18ad	G→A	IVS18a-10G→A
	In18c	C→T	IVS18c-3C→T
SREBF-2	Ex1	CTG→CTA	75G→A
	Ex10d	GCC→GCT	1782C→T	Identified in A-A control sample
	Ex18	CAT→CAC	3105T→C
	Ex18	CGG→AGG	3175C→A
	Ex19	CTG→TTG	3316C→T

^aThe reference is included for SNPs that were described previously. 

^bThe A of the initiator ATG is counted +1. Only coding sequence is counted. 

^cIntron mutation (IVS = intervening sequence) is designated by intron number and nucleotide number counted from splice donor site (positive number) or from splice acceptor site (negative number) (Antonarakis 1998). 

^dNot detected by GeneChip probe arrays. SNPs = Single nucleotide polymorphisms.