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. Author manuscript; available in PMC: 2012 Jun 15.
Published in final edited form as: J Immunol. 2011 May 9;186(12):7205–7214. doi: 10.4049/jimmunol.1002469

Figure 6. Deletion of GC-C resulted in a differential cytokine response during acute DSS-induced injury.

Figure 6

A, B. ELISA of organ culture supernatants indicated that GC-C−/− mice produced significantly less TNFα and IFNγ following acute DSS injury as compared to wildtype animals. (basal n=3–4 mice per group; acute DSS n=10–11 mice per group. *P<0.05 versus basal GC-C+/+)

C–G. A survey of cytokines and chemokines relevant to DSS-induced disease showed similar levels in wildtype and GC-C−/− mice during mucosal injury. (basal n=3–4 mice per group; acute DSS n=14–17 mice per group, *P<0.05 versus basal GC-C+/+, #P<0.05 versus basal GC-C−/−)