Table 3.
Comparison of GenomeScan-Predicted Genes on Human Chromosome 22 with Annotated Genes
| Variable | Category of gene | |||
|---|---|---|---|---|
| Known | Related | Pseudo | Other | |
| Total no. of genes annotated in Chr22 | 307 | 120 | 132 | 245 |
| Percent of annotated genes in category covered by GenomeScan-predicted genes | 95 | 88 | 67 | 67 |
| Percent of annotated genes in category overlapping multiple GenomeScan-predicted genes | 9 | 6 | 1 | 1 |
| Percent of annotated exons in category covered by GenomeScan-predicted exons | 94 | 92 | 74 | 74 |
| Percent of all GenomeScan-predicted genes which match annotated genes in category | 51 | 15 | 11 | 12 |
Genes were predicted with GenomeScan in the masked May 19, 2000 version of the Chr22 sequence, and compared to the Sanger Centre annotation (http://www.sanger.ac.uk/HGP/Chr22/cwa_archive/Release_2_19-05-2000.shtml). Known genes, related genes, predicted genes, immunoglobulin “gene segments”, and pseudogenes are distinguished in the annotation; the “Other” category includes annotated predicted genes and gene segments. GenomeScan predicted a total of 648 genes in the Chr22 sequence, of which 11% did not overlap any annotated gene; thus, the entries in the last row of the table total 89% rather than 100%.