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. 2011 Jun 8;6(6):e20216. doi: 10.1371/journal.pone.0020216

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Brim et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Extracted peptides from adenoma and normal regions were separately subjected to LC-MS-MS/MS. Data were searched against human database and analyzed by Visualize software. After stringent filtration, 161 proteins were found to be expressed by the adenoma and 105 by the normal region . Of these, 103 proteins were found to be exclusively expressed in the adenoma.