Table 1. Clinical Characteristics of 332 Children with Cardiomyopathy Listed for Heart Transplantation, by Heart Failure Severity Scores at Time of Listing.
Heart Failure Severity Score* | ||||
---|---|---|---|---|
Characteristic | 2 (n = 109) |
1 (n = 118) |
0 (n = 105) |
P |
Boys, % | 60 | 47 | 44 | 0.03 |
White, % | 69 | 62 | 73 | 0.19 |
Age (mean), y | 4.2 | 7.6 | 7.5 | <0.001 |
Age < 6 months at listing, n (%) | 34 (59) | 14 (24) | 10 (17) | <0.001 |
Body surface area at listing (mean), m2 | 0.7 | 1.0 | 0.9 | <0.001 |
Time from presentation to listing (mean), years | 0.2 | 0.6 | 1.3 | <0.001 |
Cardiomyopathy phenotype, % | ||||
Dilated | 88 | 88 | 72 | 0.003 |
Hypertrophic | 6 | 1 | 5 | 0.12 |
Restrictive | 4 | 7 | 21 | <0.001 |
LVFS (mean), z-score | −9.4 | −9.2 | −6.5 | <0.001 |
LV mass (mean), z-score | 3.2 | 2.4 | 2.3 | 0.09 |
Creatinine at listing (mean), mg/dL | 0.74 | 0.60 | 0.54 | 0.004 |
LVFS = Left ventricular factional shortening
LV = Left ventricle
2 = children on mechanical ventilatory or circulatory support; 1 = children on intravenous inotropic support without mechanical support; 0 = children on neither intravenous inotropic or mechanical support.