Table 5.
Crude means (standard deviation) and adjusted changes from baseline (Δ) for lipid profile during the follow-up by insulin resistance.
| 3 months (NIR=78 IR=43) | 6 months (NIR=68 IR=41) | 12 months (NIR=51 IR=23) | p valuea | ||||
|---|---|---|---|---|---|---|---|
| Mean (sd) | Δ a | Mean(sd) | Δ a | Mean(sd) | Δ a | ||
| Total Cholesterol (mg/dl) | |||||||
| NIR | 191.1 (38.3) | −1.5 | 184.7 (33.6) | −2.4 | 187.1 (37.4) | −4.1 | 0.75 |
| IR | 196.5 (39.5) | −0.4 | 186.9 (41.0) | −0.7 | 203.7 (36.3) | −2.9 | |
| HDL-cholesterol (mg/dl) | |||||||
| NIR | 46.9 (10.6) | 4.1 | 51.4 (11.4) | 7.6 | 55.3 (15.5) | 14.3 | 0.96 |
| IR | 44.2 (10.8) | 2.2 | 50.5 (13.4) | 6.6 | 55.9 (11.3) | 12.4 | |
| LDL-cholesterol (mg/dl) | |||||||
| NIR | 127.5 (38.0) | −5.4 | 117.4 (34.0) | −10.4 | 111.4 (34.8) | −19.6 | 0.25 |
| IR | 133.8 (39.2) | −2.2 | 124.1 (38.2) | −5.5 | 131.0 (37.3) | −12.5 | |
| VLDL-cholesterol (mg/dl) | |||||||
| NIR | 16.7 (8.6) | 0.01 | 15.9 (7.7) | 0.8 | 20.5 (10.9) | 1.9 | 0.008 |
| IR | 18.4 (11.0) | −0.5 | 16.0 (7.5) | −0.4 | 16.7 (8.8) | −1.7 | |
| Triacylglycerol (mg/dl) | |||||||
| NIR | 78.9 (40.0) | −1.4 | 75.9 (35.8) | 2.0 | 100.4 (55.3) | 7.6 | 0.008 |
| IR | 92.0 (55.2) | −2.4 | 79.9 (37.6) | −1.9 | 83.7 (43.7) | −8.3 | |
a
= Model based on repeated measures include time, insulin resistance and time × insulin resistance interaction adjusted for baseline values and intervention