Table 1.

Studies evaluating impact of physical activity on outcomes after a diagnosis of colon or rectal cancer

Author	Population	Activity Level	Median Follow-up	Survival HR (95% CI; P-value)
				Disease-specific	Overall
Haydon et al 2006 (43)	Colorectal cancer patients (all stages and both sexes)	Any regular weekly exercise vs. none at all	5.5 years from diagnosis	0.73 (0.54–1.00; P = 0.05)	0.77 (0.58–1.03; P = 0.08)
Meyerhardt et al 2006 (44)	Women with colorectal cancer (stages I to III)	18 MET-hours/week vs. < 3 MET-hours/week	9.6 years from diagnosis	0.39 (0.18–0.82; P = 0.008)	0.43 (0.35–0.74; P = 0.003)
Meyerhardt et al 2009 (45)	Men with colorectal cancer (stages I to III)	27 MET-hours/week vs. < 3 MET-hours/week	8.6 years from diagnosis	0.47 (0.24–0.92; P = 0.002)	0.59 (0.41–0.86; P <0.001)
Meyerhardt et al 2006 (46)	Colon Cancer (stage III and both sexes) receiving adjuvant therapy	18–26.9 MET-hours/week vs. < 3 MET-hours/week	3.8 years from trial entry	0.51 (0.26–1.01)	0.71 (0.32–1.59)
		≥ 27 MET-hours/week vs. < 3 MET-hours/week		0.60 (0.036–1.01; P for trend = 0.03)	0.37 (0.16–0.82; P for trend = 0.01)

Abbreviations: HR, hazard ratio; CI, confidence interval; MET, metabolic equivalent task.