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. Author manuscript; available in PMC: 2011 Jun 8.
Published in final edited form as: Chem Rev. 2008 Jun 25;108(7):2554–2584. doi: 10.1021/cr068081q

Figure 10.

Figure 10

Dopamine transients during cocaine self-administration. Left panel: dopamine increases before the lever press (time 0, solid line) and immediately after. Right panel: the cyclic voltammogram indicates the substance detected was dopamine. The solid line is the cyclic voltammogram taken at the peak of the dopamine response, and the dashed line is the cyclic voltammogram taken during electrical stimulation of the ventral tegmental area (24 pulses, 125 µA, at 60 Hz) normalized to the peak amplitude for the response at the lever press.