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. Author manuscript; available in PMC: 2011 Jun 8.
Published in final edited form as: Science. 2010 Nov 5;330(6005):831–835. doi: 10.1126/science.1191175

Fig. 2.

Fig. 2

Potent β-glucuronidase inhibitors. (A) Crystal structures of Inhibitors 2 and 3 bound to the active site of E. coli β-glucuronidase. (B) Inhibitors are observed to stack cooperatively between monomers in the E. coli β-glucuronidase tetramer. Amino acid abbreviations: D, Asp; E, Glu; F, Phe; G, Gly; L, Leu; M, Met; R, Arg; S, Ser; Y, Tyr.