Skip to main content
. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Basic Clin Pharmacol Toxicol. 2010 Feb 9;107(1):583–589. doi: 10.1111/j.1742-7843.2010.00545.x

Fig. 7.

Fig. 7

Effect of antagonistic anti-Fas antibody (ZB4) on asperfuranone in A549 cells. (A) The anti-proliferative and (B) the pro-apoptotic effect of asperfuranone was decreased by Fas antagonist ZB4. For blocking experiments, cells were pre-incubated with 250 ng/ml ZB4 for 1 hr and then treated with 20 μM of asperfuranone for 48 hr. Cell viability and apoptosis induction were examined by XTT and BD ApoAlert™ DNA Fragmentation Assay kit. The data shown are the mean ± S.D. of three determinations. The asterisk indicates a significant difference between control and asperfuranone-treated cells, as analysed by Dunnett's test(p < 0.05).