Table 1.
List of individual miRNAs involved in different steps of neural development
miRNA | Species | Target | Function | Reference |
---|---|---|---|---|
lsy-6 | C. elegans | Cog-1 | required to specify ASEL sensory neuron identity | (40) |
miR-273 | C. elegans | Die-1 | expressed in ASER; suppresses ASEL identity chemosensory neuron diff. | (12) |
let-7b | rodent | TLX cyclin D1 | regulation of neural differentiation | (104) |
miR-9 | human | REST | regulation of neurogenesis | (76) |
miR-9 | rodent | Foxg1 | regulation of neural differentiation | (87) |
miR-124 | rodents | SCP1 | regulation of neural differentiation and neurogenesis in the developing spinal cord | (94) |
miR-124 | rodents | SOX9 | regulation of the neurogenesis in the SVZ stem cell niche and neurite outgrowth in neuronal differentiation | (15) |
miR-124 | rodent | PTBP1 | regulation of neural differentiation | (70) |
miR-124 | rodent | LAMC1 ITGB1 | regulation of neural differentiation | (10) |
miR-125b | rodent | NR2A | dendrite spine development | (23) |
miR-132 | rodent | MeCP2 | neuronal homeostasis | (47) |
miR-132 | rodents | RFX4 | regulation of the circadian clock | (14) |
miR-132 | rodent | P250GAP | regulation of neuronal morphogenesis and dendrite development | (95,99) |
miR-133b | rodents | Pitx3 | regulation of the maturation of midbrain dopaminergic neurons | (44) |
miR-134 | rodents | LimK1 | regulation of the dendritic spine development | (84) |
miR-134 | rodent | Pum2 | dendrite development | (27) |
miR-138 | rodent | APT1 | spine development | (88) |
miR-196 | rodents | HOXB8 | downregulation of HOXC8, HOXD8 and HOXA7 | (102) |
miR-219 | rodent | SCOP | regulation of the circadian clock | (14) |
miR-219 | rodent | Sox6, Hes5 | regulation of oligodendrocyte differentiation and myelination | (105) |
miR-219 | rodent | Sox6, FoxJ3, ZFP238, PDGFα | regulation of oligodendrocyte differentiation and myelination | (22) |
miR-338 | rodent | Sox6, Hes5 | regulation of oligodendrocyte differentiation and myelination | (105) |
MiRNA, microRNA.