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. 2011 Jun 7;17(21):2674–2680. doi: 10.3748/wjg.v17.i21.2674

Figure 1.

Figure 1

COX-2 inhibitor NS398 showed inhibitory effects on nicotine (200 ng/mL)-induced periostin expression after 24 h of treatment. COX-2-specific inhibitor NS398 (10 μmol/L) was applied to SGC-7901 cells 6 h before nicotine (200 μg/mL) treatment. A: Western blotting bands of periostin protein in four groups of gastric cancer cells; B: Quantification analysis demonstrated significantly higher relative expression of periostin in the nicotine group than in the other three groups (P < 0.05). Notes: CON: Control; Nicotine: Treated with nicotine; NS398: Treated with COX-2-specific inhibitor NS398; Ni + NS: Combined treatment with nicotine and NS398.