Table 2.
miRNA | Known function | p | q | rank (out of 143 seed-matched motifs) | References |
---|---|---|---|---|---|
141/200a | epithelial-mesenchymal transition | 0.0018 | 0.08 | 1 | (Burk et al., 2008; Gregory et al., 2008b; Korpal et al., 2008b; Park et al., 2008) |
21 | apoptosis | 0.006 | 0.39 | 1 | (Chan et al., 2005) |
155 | B cell receptor signaling | 0.007 | 0.29 | 5 | (Thai et al., 2007) |
181 | T cell receptor signaling | 0.008 | 0.07 | 5 | (Li et al., 2007) |
34 | P53 pathway | 0.04 | 0.32 | 14 | (Chang et al., 2007; He et al., 2007; Raver-Shapira et al., 2007; Tarasov et al., 2007) |
223 | granulocyte differentiation | 0.07 | 0.62 | 15 | (Johnnidis et al., 2008) |
let-7 | non-small cell lung cancer | 0.55 | 0.63 | 68 | (Esquela-Kerscher et al., 2008; Johnson et al., 2007; Kumar et al., 2008) |
122 | cholesterol biosynthesis | 0.83 | 0.99 | 103 | (Krutzfeldt et al., 2005) |
133 | cardiac hypertrophy | 0.94 | 0.86 | 134 | (Care et al., 2007) |