Table 1.

Impaired Pml ^−/− Macrophage Activation upon Listeria monocytogenes Infection

	Lysosomes per cell (mean value)	Lysosomes in nonphagocitosing cell (mean value)	% of phagocitosing cells	Bacteria per cell (mean value)	% of bacteria not in endosomes	% of Mθ̣ morphologically activateda
WT	16.2	17.5	62	2.1	7	76
Pml−/−	7.8	7.4	25	2	25	25

Note: Total number of Mθ scored from 7 fields (3,000x-4,400x) in one electron microscopy section: wild-type (WT) = 21; Pml ^−/− = 24.

^aMacrophages were considered activated when showing extensive ruffling of the plasma membrane and a reduced nucleus/cytoplasm ratio.