Table 3.

Generalized linear regression (GEE) estimates for HAM-D scores during the study period, by symptom category

	Somatic			Cognitive-Affective
Effect	_ (SE)	Statistics	p-value	_ (SE)	Statistics	p-value
Intercept#	4.68 (0.48)			5.08 (0.66)
Time*		F2,66= 5.53	0.006		F2,33= 8.15	0.0007
Week 2	−0.92 (0.52)			−0.82 (0.59)		0.17
Week 4	−1.92 (0.58)			−2.74 (0.71)
History of mood disorder##	1.93 (0.56)	F1,32= 11.98	0.002	2.49 (0.82)	F1,32= 9.29	0.005

^*Baseline was used as reference.

^#Represents baseline Ham-D score of patients without diagnosed Depression

^##Represents mean additional score at baseline patients with Depression have above those without