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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Curr Opin Neurobiol. 2011 Mar 21;21(2):313–321. doi: 10.1016/j.conb.2011.02.008

Figure 1. Spatial spreading of small GTPase proteins during structural plasticity.

Figure 1

A. The spatial profile of activity of small GTPase proteins HRas, RhoA and Cdc42 imaged with 2-photon fluorescence lifetime imaging microscopy. Bar: 5 µm. Reprinted and modified from [9] and [11].

B. Activation of small GTPase protein normalized to the stimulated spine as a function of the contour distance from the stimulated spines (Dendritic segment at the spine neck = 0).