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a. 24-hour pharmacokinetics of an acute dose of D-serine on day 1 of treatment. b. 4-hour pharmacokinetics after 4 weeks of chronic dosing. c. Mean plasma level over 24 hours of acute and chronic D-serine during week 1 (filled bar) and week 4 (open bar) pharmacokinetics. The Week 4 pharmacokinetics session was not done in the 30 mg/kg phase.
