Fig. 6.
Hepatocytes were isolated from HIF-1β-Control and HIF-1β-Deficient mice, and exposed to room air or 1% oxygen. Seventy two hours later, (A) Glut-1, (B) FSP-1, (C) Snail, and (D) α-SMA mRNA levels were quantified by real-time PCR. aSignificantly different from hepatocytes exposed to room air (p<0.05). bSignificantly different from HIF-1β-Control hepatocytes exposed to the same concentration of oxygen (p<0.05).