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NF-κB Inhibitory Activity of Compounds Isolated from MSX 63935 (1–6).
| compound | IC50 (μM) |
|---|---|
| 15-O-desmethyl-5Z-7-oxozeaenol (1) | 0.75 |
| zeaenol (2) | >50 |
| 7-epi-zeaenol (3) | >50 |
| 7-oxozeaenol (4) | 11.5 |
| 5Z-7-oxozeaenol (5) | 0.24 |
| LL-Z1640-1 (6) | >50 |
| rocaglamide (positive control) | 0.075 |
