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. Author manuscript; available in PMC: 2011 Jun 9.
Published in final edited form as: J Am Chem Soc. 2010 Nov 10;132(44):15661–15670. doi: 10.1021/ja105825a

Figure 2.

Figure 2

A. Many sequenced glycopeptide gene clusters show a similar overall gene organization. The balhimycin, chloroeremomycin and teicoplanin gene clusters were cloned from cultured soil bacteria while the VEG and TEG gene clusters were cloned directly from soil. Open reading frames have been color coded according their predicted functions. B. Glycopeptide gene clusters recovered from the CA eDNA mega-library are shown. C. AZ205, a tailoring enzyme-rich eDNA cosmid clone, recovered from the AZ library is shown. Dashed lines are used to indicate the region from each gene cluster that corresponds to the tailoring enzyme-rich clone used in this study.