Table 5. Association of miR-34b/c methylation pattern with clinocopathological features in faecal specimen.
|
Faecal samples
|
||||
|---|---|---|---|---|
|
miR-34b-c
|
||||
| n=79 | Methylated | Unmethylated | P-values | |
| Sex | 28 | |||
| Male | 13 | 10 | 3 | |
| Female | 15 | 11 | 4 | P=0.8268 |
| Tumour location | 28 | |||
| Proximal colon | 7 | 4 | 3 | |
| Distal colon and rectum | 21 | 17 | 4 | P=0.497 |
| pTNM stage | 28 | |||
| 0 | 5 | 3 | 2 | |
| I | 2 | 2 | 0 | |
| II | 6 | 3 | 3 | |
| III | 3 | 2 | 1 | |
| Unknown | 9 | 8 | 1 | |
| Unclassified | 1 | 1 | 0 | |
| a | 2 | 2 | 0 | P=0.5055 |
| High-grade dysplasia | 12 | 2 | 10 | |
| Normal colon mucosa/ control patients | 39 | 5 | 34 | P<0.0001* |
a
Histology report not available, as the patients underwent chemoradiotheraphy or underwent surgery at a different location.
*P-value indicative significant data produced.