Figure 1.

Sequence alignment of sheep AANAT, seabream AANAT1a and seabream AANAT2. The alignment starts in residue 30 of the sheep AANAT, in residue 25 of the seabream AANAT1a, and in residue 28 of the seabream AANAT2. The coloring of the alignment follows the sequence similarity between AANAT1a or AANAT2 and the sequence of the sheep AANAT; identical residues are shaded and colored in white, similar residues are shaded. The secondary structure elements, as analyzed by Hickman et al. [15] and Dyda et al. [2], are shown above the residues. The mutation sites are boxed. The pairwise alignment was done using the Needle alignment tool.