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. 2011 May 24;104(12):1840–1847. doi: 10.1038/bjc.2011.175

Table 2. Pathologic variables in patients undergoing preoperative chemotherapy±radiation therapy for gastric and gastrooesophageal junction adenocarcinoma, followed by R0 resection.

  Number (%)
 
Variable Non-pCR patients (n=549) pCR patients (n=60) P-value
pT stage a
 T0b 11 (2) 60 (100)  
 T1a 21 (4) 0  
 T1b 48 (9) 0  
 T2 125 (23) 0 N/A
 T3 243 (44) 0  
 T4a 93 (17) 0  
 T4b 8 (1) 0  
       
pN stage a
 N0 241 (44) 60 (100)  
 N1 131 (24) 0  
 N2 97 (18) 0 N/A
 N3a 59 (11) 0  
 N3b 21 (4) 0  
       
Extent of surgical lymphadenectomy
 D1 20 (4) 1 (2)  
 D2 513 (93) 57 (95) 0.72c
 D3 16 (3) 2 (3)  
Number of positive LN (for ⩾N1; mean, IQR) 3.0 (1–8) 0 (0) N/A
Number of LN examined (mean, IQR) 23 (15–29) 29 (25–32) 0.04d
Pathologic treatment effect (mean %, IQR) 45 (10–95) 100 N/A

Abbreviations: IQR=interquartile range; LN=lymph node; N/A=not applicable (no statistical analysis performed, as differences are defined by subgroup stratification); pCR=pathologic complete response.

a

AJCC 7th edn, 2010.

b

T0N1 (n=9) and T0N2 (n=2) – 1 patient has recurred after a median follow-up of 17 months.

c

χ2 text.

d

Wilcoxon rank sum test with continuity correction. Bold values indicate significant differences.