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Methylation patterns of the ALDH1L1 CpG island in human tissues and cell lines. Individual CpG dinucleotides (positioned sequentially) are as follows: open circles = nonmethylated; closed circles = methylated; gray circles = methylated in one of the alleles (10 to 15 clones for each fragment were analyzed). Schematic at the bottom allows the assignment of CpGs to 1 of the 3 ALDH1L1 regions (promoter, exon 1, or intron 1).
