Table 3.
Translocations | Oncofusion protein | Frequency of occurrence(% of AML) |
---|---|---|
t(8;21) | AML1-ETO | 10% |
t(15;17) | PML-RARα | 10% |
inv(16) | CBF□-MYH11 | 5% |
der(11q23) | MLL-fusions | 4% |
t(9;22) | BCR-ABL1 | 2% |
t(6;9) | DEK-CAN | <1% |
t(1;22) | OTT-MAL | <1% |
t(8;16) | MOZ-CBP | <1% |
t(7;11) | NUP98-HOXA9 | <1% |
t(12;22) | MN1-TEL | <1% |
inv(3) | RPN1-EVI1 | <1% |
t(16;21) | FUS-ERG | <1% |