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Acute Myeloid Leukemia (AML)–Associated Oncofusion Proteins
| Translocations | Oncofusion protein | Frequency of occurrence(% of AML) |
|---|---|---|
| t(8;21) | AML1-ETO | 10% |
| t(15;17) | PML-RARα | 10% |
| inv(16) | CBF□-MYH11 | 5% |
| der(11q23) | MLL-fusions | 4% |
| t(9;22) | BCR-ABL1 | 2% |
| t(6;9) | DEK-CAN | <1% |
| t(1;22) | OTT-MAL | <1% |
| t(8;16) | MOZ-CBP | <1% |
| t(7;11) | NUP98-HOXA9 | <1% |
| t(12;22) | MN1-TEL | <1% |
| inv(3) | RPN1-EVI1 | <1% |
| t(16;21) | FUS-ERG | <1% |
