Table 3.
Distribution of Ku70 promoter T-991C genotypes stratified by age and gender in the gastric cancer and control groups
| Case (%) | Control (%) | Adjusted ORa (95% CI) | P-value | |
|---|---|---|---|---|
| Age | ||||
| < 55 | ||||
| TT | 52 (80.0) | 238 (90.8) | 1.00 (ref) | |
| TC | 11 (16.9) | 22 (8.4) | 2.18 (0.97-4.88) | 0.0600 |
| CC | 2 (3.1) | 2 (0.8) | 4.31 (0.69-27.33) | 0.1551 |
| ≥ 55 | ||||
| TT | 54 (76.1) | 264 (88.6) | 1.00 (ref) | |
| TC | 15 (21.1) | 30 (10.1) | 2.52 (1.37-4.68) | 0.0139 |
| CC | 2 (2.8) | 4 (1.3) | 2.61 (0.51-11.62) | 0.2776 |
| Gender | ||||
| Male | ||||
| TT | 69 (76.7) | 336 (89.1) | 1.00 (ref) | |
| TC | 18 (20.0) | 36 (9.6) | 2.58 (1.33-4.47) | 0.0085 |
| CC | 3 (3.3) | 5 (1.3) | 2.85 (0.71-11.36) | 0.1477 |
| Female | ||||
| TT | 37 (80.4) | 166 (90.7) | 1.00 (ref) | |
| TC | 8 (17.4) | 16 (8.7) | 2.13 (0.79-6.03) | 0.1019 |
| CC | 1 (2.2) | 1 (0.6) | 4.07 (0.31-69.45) | 0.3371 |
a Adjusted by age and gender when appropriate; the line with ORs that significantly differ from 1.00 are bolded