Table 2. Top 50 most associated genes with the EA in 9538 individuals.
rank | Chr. | Gene | Number of SNPs | Start position | Stop position | P-value |
1 | 16 | FLJ41766 | 35 | 21219670 | 21237413 | 1.40E-05 |
2 | 16 | CRYM | 64 | 21177342 | 21221918 | 2.10E-05 |
3 | 16 | ANKS4B | 82 | 21152516 | 21171251 | 2.80E-05 |
4 | 10 | NPM3 | 24 | 103531071 | 103533148 | 6.10E-05 |
5 | 10 | FGF8 | 22 | 103519876 | 103525817 | 8.80E-05 |
6 | 10 | MGEA5 | 31 | 103534198 | 103568165 | 0.000117 |
7 | 14 | LTB4R2 | 110 | 23848000 | 23850798 | 0.000154 |
8 | 10 | HPS6 | 12 | 103815136 | 103817783 | 0.000155 |
9 | 14 | C14orf21 | 115 | 23838937 | 23844214 | 0.000171 |
10 | 14 | ADCY4 | 122 | 23857409 | 23873704 | 0.000175 |
11 | 19 | ZNF100 | 83 | 21698682 | 21742270 | 0.000232 |
12 | 14 | RABGGTA | 76 | 23804583 | 23810643 | 0.000237 |
13 | 5 | DUSP1 | 108 | 172127706 | 172130809 | 0.000249 |
14 | 10 | CC2D2B | 80 | 97749872 | 97782431 | 0.000263 |
15 | 14 | TGM1 | 80 | 23788159 | 23802256 | 0.000319 |
16 | 10 | KCNIP2 | 29 | 103575720 | 103593667 | 0.000538 |
17 | 1 | ZBTB37 | 53 | 172104115 | 172122397 | 0.000553 |
18 | 1 | DARS2 | 45 | 172060580 | 172094305 | 0.000617 |
19 | 18 | CABYR | 76 | 19972952 | 19995562 | 0.000629 |
20 | 10 | CCNJ | 84 | 97793143 | 97810612 | 0.000723 |
21 | 17 | DYNLL2 | 49 | 53515797 | 53521810 | 0.000783 |
22 | 11 | FLRT1 | 99 | 63627937 | 63643221 | 0.000844 |
23 | 10 | C10orf76 | 89 | 103595345 | 103805922 | 0.000847 |
24 | 7 | C7orf59 | 44 | 99584465 | 99589769 | 0.000872 |
25 | 11 | BBS1 | 64 | 66034694 | 66057660 | 0.000953 |
26 | 19 | ZNF99 | 88 | 22730846 | 22744624 | 0.000961 |
27 | 11 | ACTN3 | 56 | 66070966 | 66087373 | 0.001017 |
28 | 7 | C7orf43 | 41 | 99589978 | 99594238 | 0.00102 |
29 | 17 | CCDC43 | 45 | 40110330 | 40122691 | 0.001079 |
30 | 11 | CTSF | 50 | 66087510 | 66092623 | 0.001108 |
31 | 14 | NFATC4 | 104 | 23907093 | 23918650 | 0.001127 |
32 | 11 | DPP3 | 54 | 66004455 | 66033706 | 0.00114 |
33 | 11 | ZDHHC24 | 57 | 66063310 | 66070247 | 0.00117 |
34 | 15 | RHCG | 89 | 87815643 | 87840803 | 0.001346 |
35 | 3 | APEH | 52 | 49686438 | 49695938 | 0.00135 |
36 | 7 | GAL3ST4 | 52 | 99594800 | 99604309 | 0.001364 |
37 | 1 | SERPINC1 | 57 | 172139564 | 172153096 | 0.001451 |
38 | 7 | BET1 | 79 | 93458935 | 93471626 | 0.001466 |
39 | 3 | RHOA | 51 | 49371582 | 49424530 | 0.001497 |
40 | 17 | SPHK1 | 52 | 71892296 | 71895536 | 0.001549 |
41 | 3 | MST1 | 48 | 49696391 | 49701099 | 0.001573 |
42 | 18 | CD226 | 199 | 65681172 | 65775212 | 0.00158 |
43 | 3 | RNF123 | 53 | 49701993 | 49733966 | 0.00163 |
44 | 5 | C5orf39 | 57 | 43074938 | 43076098 | 0.00166 |
45 | 11 | PELI3 | 39 | 65990911 | 66001384 | 0.001683 |
46 | 6 | LY6G6F | 110 | 31782662 | 31786351 | 0.00177 |
47 | 3 | BSN | 87 | 49566925 | 49683986 | 0.001818 |
48 | 7 | STAG3 | 50 | 99613473 | 99649946 | 0.00182 |
49 | 6 | BAT5 | 131 | 31762714 | 31779067 | 0.00186 |
50 | 6 | LY6G6C | 97 | 31794403 | 31797489 | 0.00188 |