Table 3. miRNA targets with fold changes (up or down) ≥4 and with a p<6.8×10−5 for the various group comparison performed.
| Probe | Chromosomal Position | Aden vs N | P1 vs N | P2 vs N | D1 vs N | D2 vs N | P1 vs Aden | P2 vs Aden | D1 vs Aden | D2 vs Aden | P1 vs D1 | P1 vs P2 | D1 vs D2 |
| HS_29 | 2p13 | 1.08 (6.1e-01) | 1.96 (3.0e-09) | 1.98 (6.9e-03) | 3.64 (1.0e-13) | 4.18 (2.4e-07) | 1.82 (3.2e-05) | 1.84 (2.0e-02) | 3.37 (2.7e-10) | 3.88 (1.7e-06) | −1.85 (1.4e-06) | −1.01 (9.6e-01) | −1.16 (5.1e-01) |
| hsa-miR-135b | 1q32.1 | 6.89 (9.4e-22) | 6.06 (7.2e-26) | 6.06 (7.6e-14) | 5.17 (8.8e-21) | 4.58 (6.5e-12) | −1.14 (1.7e-01) | −1.14 (4.6e-01) | −1.33 (1.0e-02) | −1.51 (2.0e-02) | 1.16 (9.7e-02) | −1.01 (9.5e-01) | 1.08 (6.5e-01) |
| hsa-miR-31 | 9p21.3 | 4.76 (2.4e-12) | 4.6 (1.7e-17) | 4.21 (2.0e-06) | 12.04 (2.0e-21) | 8.35 (1.6e-10) | −1.04 (8.0e-01) | −1.13 (6.5e-01) | 2.53 (1.2e-06) | 1.75 (4.0e-02) | −2.66 (3.0e-10) | 1.08 (7.5e-01) | 1.34 (2.4e-01) |
| hsa-miR-552 | 1p34.3 | 3.51 (1.7e-10) | 3.48 (8.3e-14) | 3.72 (7.9e-07) | −1.59 (1.8e-03) | −1.24 (3.3e-01) | −1.01 (9.5e-01) | 1.06 (8.0e-01) | −5.56 (6.0e-15) | −4.35 (6.0e-08) | 5.51 (2.2e-18) | −1.04 (8.8e-01) | −1.25 (3.4e-01) |
| hsa-miR-592 | 7q31.33 | 1.89 (9.0e-06) | 1.67 (5.1e-07) | 1.97 (1.9e-03) | −2.27 (3.3e-09) | −1.76 (6.7e-03) | −1.13 (2.6e-01) | 1.04 (8.5e-01) | −4.29 (1.1e-14) | −3.33 (6.0e-07) | 3.69 (2.7e-16) | −1.2 (4.0e-01) | −1.23 (3.4e-01) |
| hsa-miR-1 | 18q11.2∶20q13.33 | −4.64 (1.2e-12) | −3.59 (1.0e-15) | −3.54 (1.1e-05) | −6.29 (2.4e-17) | −4.46 (3.1e-07) | 1.29 (6.9e-02) | 1.31 (3.1e-01) | −1.36 (6.2e-02) | 1.04 (8.8e-01) | 1.84 (1.7e-05) | 1.03 (9.2e-01) | −1.45 (1.6e-01) |
| hsa-miR-137 | 1p21.3 | −10 (1.2e-29) | −5.3 (3.3e-30) | −5.5 (1.2e-16) | −5.19 (7.6e-26) | −5.49 (5.2e-17) | 1.89 (1.8e-11) | 1.82 (6.2e-05) | 1.93 (5.2e-10) | 1.82 (4.6e-05) | −1.03 (7.0e-01) | 1.03 (8.5e-01) | 1.05 (7.1e-01) |
| hsa-miR-9 | 1q22∶5q14.3∶15q26.1 | −4.43 (1.4e-16) | −3.77 (5.4e-23) | −3.38 (1.4e-07) | −4.44 (1.0e-19) | −2.05 (4.4e-04) | 1.18 (1.3e-01) | 1.31 (1.9e-01) | −1 (9.8e-01) | 2.16 (3.4e-04) | 1.22 (2.9e-02) | −1.08 (6.9e-01) | −2.18 (1.7e-04) |
| hsa-miR-99a | 21q21.1 | −4.9 (2.2e-18) | −1.42 (1.2e-05) | −1.35 (1.0e-01) | −1.99 (3.8e-09) | −1.59 (1.1e-02) | 3.44 (1.7e-16) | 3.62 (1.6e-08) | 2.46 (3.3e-10) | 3.09 (1.8e-07) | 1.43 (1.6e-04) | −1.03 (8.9e-01) | −1.26 (2.1e-01) |
Values in table correspond to the average fold change on the raw scale observed for the indicated comparison. All fold changes are reported as values >1.0, where “+” indicates up-regulation and “−” indicates down-regulation relative to the second group listed in the column title, p-values are listed in parentheses. Up-regulated and down-regulated values with fold change ≥4 and with p<6.8×10−5 are highlighted in bold.