Table 2. Cell growth inhibitory activity of 9NC and 9NC-LP in human cancer and normal cells.
Incubation time | IC50(µmol/L)a | |||||||
HepG2 | Bel-7402 | Hep 3B | L02 | |||||
9NC | 9NC-LP | 9NC | 9NC-LP | 9NC | 9NC-LP | 9NC | 9NC-LP | |
10 h | 29.39±1.26 | 37.56±1.78 | 34.05±0.95 | 46.8±1.39 | 346.36±14.96 | 367.81±20.33 | 39.94±0.93 | 51.43±2.45 |
24 h | 16.33±0.72 | 18.81±0.89 | 17.46±1.03 | 18.00±0.94 | 275.15±11.58 | 290.41±18.71 | 17.87±0.63 | 23.90±0.36 |
48 h | 6.28±0.12 | 1.53±0.08 | 6.83±0.29 | 1.61±0.04 | 17.19±1.34 | 34.39±1.52 | 29.14±0.52 | 14.52±0.48 |
72 h | 0.17±0.01 | 0.02±0.00 | 0.41±0.01 | 0.29±0.01 | 7.28±0.43 | 18.56±0.52 | 12.58±0.08 | 2.66±0.05 |
IC50, the concentration that inhibits cell growth by 50%.