Table 1. The clinical features of the high myopia family 951 with a ZNF644 gene mutation.

Subject No.	Age (Yr)*	Gender	Axial length (mm)**		Refractive errors (DS)**		Fundus appearance**		ZNF644 mutation***
			OD	OS	OD	OS	OD	OS	Nucleotide change	Amino acid change
III:1	71	M	23.8	23.9	0	−0.22	normal	normal	2156 A	S672
III:2	68	F	28.6	29.5	−11.5	−13.02	tigroid or tesselated	tigroid or tesselated	2156 A>G	S672G
III:3	73	F	30.5	31.1	−16.3	−20.04	tigroid or tesselated	tigroid or tesselated	2156 A>G	S672G
III:4	74	M	24	24.3	0	0	normal	normal	2156 A	S672
III:5	65	M	27.1	28.2	−9.27	−11.02	tigroid or tesselated	tigroid or tesselated	2156 A>G	S672G
III:7	70	M	23.7	24	−0.5	−0.5	normal	normal	2156 A	S672
III:9	65	F	23.9	24.1	0.23	0	normal	normal	2156 A	S672
IV:1	38	M	24.5	24.3	0	0	normal	normal	2156 A	S672
IV:2	27	F	26.5	27.2	−7.53	−9.49	normal	normal	2156 A>G	S672G
IV:3	25	M	28.9	29.4	−12.11	−12.31	normal	normal	2156 A>G	S672G
IV:4	32	F	24.1	25.2	−0.38	−0.5	normal	normal	2156 A	S672
IV:5	36	M	24.9	24.8	−0.46	−0.42	normal	normal	2156 A	S672
IV:6	34	F	24.8	25	−0.48	−0.5	normal	normal	2156 A	S672
IV:7	31	F	24.8	24.9	−0.32	−0.44	normal	normal	2156 A	S672
IV:8	34	M	24.3	24.2	−0.2	0.2	normal	normal	2156 A	S672
IV:9	36	M	23.9	23.8	0.25	0.4	normal	normal	2156 A	S672
IV:10	30	F	24.9	25.2	−0.1	−0.12	normal	normal	2156 A	S672
V:1	8	F	26.9	26	−9.54	−6.34	normal	normal	2156 A>G	S672G
V:2	6	M	24.3	24.2	0.22	0.15	normal	normal	2156 A	S672

*The age when the family member was recruited in 2009.

**OS, left eye; OD, right eye; DS, diopter sphere.

***Location: chromosome 1: 9117748 (exon 3 of ZNF644 gene).