Table 2.
Top Accuracy Genes Selected by LDA and Class Prediction Method for Classifying BRCA2 Mutation Positive Tissue Samples
| Colon | Description | Accuracy |
|---|---|---|
| LDA | ||
| 175123 | mitogen-activated protein kinase 7 | 1.000000 |
| 714106 | plasminogen activator, urokinase | 0.954545 |
| 210887 | suppression of tumorigenicity 13 (colon carcinoma) | 0.954545 |
| 29054 | ARP1 (actin-related protein 1, yeast) homolog A | 0.954545 |
| 36775 | hydroxyacyl-Coenzyme A dehydrogenase | 0.954545 |
| 21652 | catenin (cadherin-associated protein), alpha 1 (102kD) | 0.909091 |
| 233721 | insulin-like growth factor binding protein 2 (36kD) | 0.909091 |
| 666377 | zinc finger protein 161 | 0.909091 |
| 50413 | armadillo repeat gene deletes in velocardiofacial syndrome | 0.909091 |
| 179804 | PWP2 (periodic tryptophan protein, yeast) homolog | 0.909091 |
| 563444 | forkhead (Drosophila)-like 5 | 0.909091 |
| 345423 | DKFZP564M112 protein | 0.909091 |
| 246194 | ESTs | 0.909091 |
| 23014 | mitogen-activated protein kinase 1 | 0.909091 |
| 51209 | protein phosphatase 1, catalytic subunit, beta isoform | 0.909091 |
| 341130 | retinoblastoma-like 2 (p130) | 0.909091 |
| 345645 | plate-derived growth factor beta polypeptide | 0.909091 |
| Class Prediction Method (Hedenfalk et al. 2001) | ||
| 36775 | hydroxyacyl-Coenzyme A dehydrogenase | 0.954545 |
| 29054 | ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) | 0.954545 |
| 666377 | Zinc finger protein 161 | 0.909091 |
| 50413 | armadillo repeat gene deletes in velocardiofacial syndrome | 0.909091 |
| 31842 | UDP-galactose transporter related | 0.863636 |
| 51209 | protein phosphatase 1, catalytic subunit, beta isoform | 0.909091 |
| 345645 | plate-derived growth factor beta polypeptide | 0.909091 |
| 340644 | integrin, beta 8 | 0.863636 |
| 344109 | proliferating cell nuclear antigen | 0.863636 |
| 784830 | D123 gene product | 0.772727 |
| 366824 | cyclin-dependent kinase 4 | 0.727273 |