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. 2011 Feb 25;12(3):1505–1518. doi: 10.3390/ijms12031505

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© 2011 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 3. — Biomarker scores can be used for the prognosis of melanoma. Serum samples from melanoma patients were tested for elevated levels of IL-8 and Cathepsin B. High mortality group: patients died within 3 years after enrollment of the study; Low mortality group: patients survived for more than 3 years after enrollment of the study. Patients were scored based on the initial serum levels of IL-8 and Cathepsin B. Patients receive 0 score for normal levels, 1 score for elevated levels of only one biomarker and 2 scores if both were elevated. Patients in the High mortality group showed significantly higher scores as judged by unpaired t test. Data were presented as mean ± SEM.