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Aortic ring isometric tension recording. Relaxation to carbachol in % of phenylephrine (Phe)-induced contraction was assessed in aortic rings. Apolipoprotein-E-deficient (ApoE−/−) mice were treated with ramipril (R), or telmisartan (T) or in combination (T/R). Data shown are means ± SEM from seven to ten animals per group. *P < 0.05, different from values for ApoE−/− mice.
