Table 2.

Phenylephrine-induced contraction of corpora cavernosal strips and aortic rings

% tension at baseline	Wild-type	ApoE−/−	ApoE−/−+ ramipril	ApoE−/−+ telmisartan	ApoE−/−+ telmisartan/ramipril
Aortic tissue
Carbachol	19.03 ± 0.97	22.63 ± 2.10	20.93 ± 3.40	24.47 ± 2.14	22.20 ± 0.92
GTN	20.41 ± 2.64	20.00 ± 1.88	20.80 ± 2.28	27.02 ± 3.21	27.01 ± 1.78
Cavernosal tissue
Carbachol	7.69 ± 0.55	9.68 ± 0.78	10.41 ± 0.89	10.23 ± 1.68	8.78 ± 1.32
GTN	9.44 ± 0.81	11.22 ± 0.89	11.14 ± 1.57	10.58 ± 1.57	9.83 ± 1.50

Contractile responses (% of baseline tension) of aortic and cavernosal tissue to phenylephrine before relaxation with carbachol or GTN. No significant difference within all treatment groups (n.s.). Five to ten animals per group. Mean ± SEM.

ApoE^−/−, apolipoprotein-E-deficient; GTN, glyceryl trinitrate.