Figure 4.

Effect of resveratrol pretreatment on CFTR expression and localization in CFPAC1 cells. Confocal fluorescence immunocytochemical representative images (from five experiments, each performed in duplicate) of CFTR distribution in (A) control (DMSO-treated) and (B) resveratrol-treated (50 µM, 18 h) CFPAC1 cells. Bar: 20 µm. Note the increased staining at the (peri)-membrane in resveratrol-treated cells (indicated by arrows). CFTR, cystic fibrosis transmembrane conductance regulator; CFPAC1, cystic fibrosis pancreatic adenocarcinoma.