Table 2.

Comparison of baseline characteristics of the patients operated on during the first 5 years and the patients operated on during the second 5 years

	First 5 years (n = 18)	Second 5 years (n = 22)	Significance
Gender (% male)	8 (44%)	11 (50%)	p = 0.76
Age (years)	46.2 (±11.0)	48.4 (±11.9)	p = 0.56
BMI (kg/m2)	29.8 (±4.4)	26.6 (±5.3)	p = 0.32
Preoperative medication	13 (72%)	20 (91%)	p = 0.12
Adenoma diameter (cm)	16.9 (±7.8)	20.9 (10.4)	p = 0.18
Invasion on preoperative MRI	7 (39%)	12 (54%)	p = 0.32
Preoperative IGF-1 value (nmol/l)	93.3 (±23.5)	116.6 (±36.9)	p = 0.03

Data are expressed as means and standard deviations in case of continuous variables and as exact numbers and percentages in case of nominal or ordinal variables. BMI: Body mass index; IGF-1: insulin-like growth factor-1; MRI: magnetic resonance imaging