Skip to main content
. 2011 Feb 24;153(7):1391–1399. doi: 10.1007/s00701-011-0959-8

Table 4.

Review of the criteria to define remission of acromegaly and remission percentages in macroadenomas reported in the most recently published series (1997–2005)

Author N Criteria of remission Remission %
van Lindert et al. [45] 40 GH <2 ng/ml after OGTT, IGF1 N 55
Abosch et al. [2] 254 Basal GH <5 ng/ml 71
Swearingen et al. [41] 129 GH <2 ng/ml after OGTT or IGF1 N or basal GH <2.5 ng/ml 48
Gittoes et al. [18] 45 GH <2 mU/l after OGTT or basal GH <5 mU/l 51
Laws et al. [29] 51 GH ≤1 ng/ml after OGTT or IGF1 N or basal GH ≤2.5 ng/ml 51
Kaltsas et al. [23] 50 Basal GH <2.5 ng/ml, IGF1 N 26
Abe and Ludecke [1] 126 Basal GH <2.5 ng/ml, IGF1 N 68
Shimon et al. [40] 44 GH <2 ng/ml basal or after OGTT, IGF1 N 64
Beauregard et al. [4] 77 GH ≤1 ng/ml after OGTT or IGF1 N or basal GH ≤2.5 ng/ml 49
Trepp et al. [43] 64 GH <1 ng/ml after OGTT or IGF1 N or basal GH <2.5 ng/ml 39
Erturk et al. [15] 19 GH ≤2 ng/ml basal or after OGTT 15
Nomikos et al. [34] 364 GH <1 ng/ml after OGTT or IGF1 N or GH <2.5 ng/ml 50

N: number of patients included; GH: growth hormone; OGTT: oral glucose tolerance test; IGF1: insulin-like growth factor type 1