. 2011 Jul;52(7):1373–1382. doi: 10.1194/jlr.M013391

TABLE 3.

Indirect calorimetry results over 24 h

Parameter	Control^b	OEA (0.1 g/kg BW)^b	KDS-5104 (0.1 g/kg BW)^b
ANOVA on repeated measure over 24 h
LOX (watt/kg mouse) raw	11.26 ± 0.24^a	13.92 ± 0.26^b	12.43 ± 0.23^b
Adjusted for activity	11.18 ± 0.1^a	13.88 ± 0.1^b	12.31 ± 0.1^b
GOX (watt/kg mouse) raw	5.401 ± 0.12^a	4.01 ± 0.12^b	4.474 ± 0.10^b
Adjusted for activity	5.57 ± 0.03^a	3.98 ± 0.03^a	4.53 ± 0.03^a
LOX ratio raw	0.63 ± 0.01^a	0.72 ± 0.01^b	0.69 ± 0.01^b
Adjusted for activity	0.63 ± 0.01^a	0.67 ± 0.01^b	0.70 ± 0.01^b
EE (watt/kg mouse) raw	16.58 ± 0.1^a	17.81 ± 0.1^b	16.85 ± 0.1^a
Adjusted for activity	16.7 ± 0.01^a	17.7 ± 0.01^b	16.7 ± 0.01^a
Total activity (AU)^a	198 ± 10^a	429 ± 64^b	449 ± 54^b
ANOVA of postprandial period
LOX ratio raw^c	0.51 ± 0.04^a	0.66 ± 0.06^a,b	0.69 ± 0.05^b
GOX ratio raw	0.49 ± 0.04^a	0.34 ± 0.06^a,b	0.31 ± 0.05^b

Results are means ± SEM (N = 10 mice per group). Postprandial period lasting from feeding completion to 600 min afterward (from 396 to 1,008 min after the introduction of the mouse in the calorimetric system).

For total activity, the P value for time effect was 0.0192, and the P value for treatment effect was 0.0039; time × treatment is nonsignificant. Total activity corresponds to the sum of rearing and spontaneous activity, normalized to the control mice mean value.

Values in the same row and not sharing the same superscripted letter (^{a, b}) are statistically different (P ≤ 0.05). The values and statistical indications after adjustment on total spontaneous activity are indicated.

cthinsp: LOX ratio = LOX/(LOX + GOX).