Table 2.
Reported levels of production and yields of self-assembling peptides produced using recombinant systems.
Peptide | Host | Fusion protein yield (mg/L) | Theoretical peptide yield (mg/L) | Peptide purified (mg/L) | Efficiency of peptide purification (%) | Reference |
---|---|---|---|---|---|---|
Aβ11–26 | Escherichia coli | 80 | 27 | 10 | 37 | [27] |
RADA | Ralstonia eutropha | 433 | 116 | 10.1 | 8.7 | [28] |
SA2 | Escherichia coli | 300 | 30 | 30 | 100 | [29] |
P11−2 | Escherichia coli | 85 | 6.8 | 2.63 | 38.7 | [17] |
P11−2 | Escherichia coli | 330 | 32.1 | 13 | 40.5 | [20] |
P11−4 | Escherichia coli | 2500 | 530 | 90 | 17 | [18] |
P11−2 | Pichia pastoris | 800–1000 | 45 | – | – | [30] |
P11−14 | Pichia pastoris | 600–700 | 75 | – | – | [30] |
P11−4 | Escherichia coli | 4640 | 371.2 | 203 | 59.5 | This study |