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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Inflamm Bowel Dis. 2011 Mar 4;17(12):2443–2455. doi: 10.1002/ibd.21672

Figure 5. Ileal Epithelial Cell CCL25 Expression is Up-regulated after GM-CSF Neutralization and NSAID Exposure.

Figure 5

(A) Immunohistochemistry for CCL25 was performed on ileal samples obtained at the time of sacrifice wild type (WT) or card15 deficient mice (C15KO) on regular chow, animals pre-treated with an IgG isotype control or a neutralizing GM-CSF antibody (GM-CSF Ab, 50 mcg, IP) on chow containing the NSAID piroxicam (PIR, 200 ppm). A negative control employed isotype sera instead of antibody (shown as insert). (B) Intestinal epithelial cells (IEC) expressing CCL25 were determined in 10 high powered fields and divided by the total number of IEC to determine the frequency of CCL25+ IEC. n=6 per group, data are shown as the mean ± SEM.