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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Neurobiol Aging. 2011 Feb 18;33(7):1237–1252. doi: 10.1016/j.neurobiolaging.2011.01.003

Figure 5. Regional amyloid deposition is associated with failure of normal habituation in the default network.

Figure 5

Mean modulation of functional response over encoding trials, calculated as the change in beta weight between the last and first encoding trial in young, individuals with low amyloid burden (PiB −) and individuals with high amyloid burden (PiB +) in left posteromedial cortex. Correlation between the change in the mean beta weight between the first and the last encoding trial and amyloid deposition in precuneus (corrected for age); r=-.39, p=0.019. Individuals with low amyloid burden (circles) and high amyloid burden (squares).