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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2011 Apr 5;20(6):1238–1250. doi: 10.1158/1055-9965.EPI-11-0005

Figure 2. Meta-Analysis of the Association Between Telomere Length and Cancer.

Figure 2

Studies included in the meta-analysis were selected based on the following criteria: DNA derived from blood and buccal cells, and analysis by quartiles of TL among controls. Unadjusted odds ratios were used to conduct analysis (exception: Pooley et al. [25]: ORs are adjusted for batch to avoid confounding). Significant study heterogeneity was present (I2=94.3%, P<0.001), so the random effects meta-analysis was used. The weight percents are from the random effects analysis. The dashed line indicates the OR of the metaanalysis. (14), (19), and (30) reported a significant association of longer TL and risk of breast cancer and NHL, respectively; we used the inverse log odds ratios to compute the summary OR.

The forest plot was created using Stata version 11.0 (StataCorp, College Station, TX). Abbreviations: OR, odds ratio; CI, confidence interval; NHL, non-Hodgkin Lymphoma.